Endocrine Abstracts

Background: Surgery is the main therapeutic option for advanced endometrial cancer; however, when disease relapses, chemotherapy is the only option. Chemoresistance is a very common phenomenon in these tumors. We previously demonstrated that GH protects breast cancer cells towards the cytotoxic effects of doxorubicin, inducing chemoresistance. Recent evidences show that endometrial cancer cells secrete GH, stimulating their own growth in an autocrine fashion.<p class="abst...

Background: During the last decade, radiofrequency ablation (RFA) has emerged as a reliable alternative to surgery for the treatment of benign symptomatic thyroid nodules in terms of effectiveness and safety.Aim: The aim of this study were: (i) to evaluate the long-term efficacy (5 years) of RFA for the treatment of benign thyroid nodules, in terms oftechnical success and nodule regrowth, and (ii) to identify the predictive factors of t...